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 Modular Representation of Layered Neural Networks

   

Layered neural networks have greatly improved the performance of various applications including image processing, speech recognition, natural language processing, and bioinformatics. However, it is still difficult to discover or interpret knowledge from the inference provided by a layered neural ne…


 Indexing the Event Calculus with Kd-trees to Monitor Diabetes

Personal Health Systems (PHS) are mobile solutions tailored to monitoring patients affected by chronic non communicable diseases. A patient affected by a chronic disease can generate large amounts of events. Type 1 Diabetic patients generate several glucose events per day, ranging from at least 6 e…


 A Workflow for Visual Diagnostics of Binary Classifiers using Instance-Level Explanations

Human-in-the-loop data analysis applications necessitate greater transparency in machine learning models for experts to understand and trust their decisions. To this end, we propose a visual analytics workflow to help data scientists and domain experts explore, diagnose, and understand the decision…


 Upper Bound of Bayesian Generalization Error in Non-negative Matrix Factorization

  

Non-negative matrix factorization (NMF) is a new knowledge discovery method that is used for text mining, signal processing, bioinformatics, and consumer analysis. However, its basic property as a learning machine is not yet clarified, as it is not a regular statistical model, resulting that theore…


 Recognizing Detailed Human Context In-the-Wild from Smartphones and Smartwatches

The ability to automatically recognize a person’s behavioral context can contribute to health monitoring, aging care and many other domains. Validating context recognition in-the-wild is crucial to promote practical applications that work in real-life settings. We collected over 300k minutes …


 Toward Scalable Machine Learning and Data Mining: the Bioinformatics Case

 

In an effort to overcome the data deluge in computational biology and bioinformatics and to facilitate bioinformatics research in the era of big data, we identify some of the most influential algorithms that have been widely used in the bioinformatics community. These top data mining and machine le…


 Multi-Label Classification of Patient Notes a Case Study on ICD Code Assignment

In the context of the Electronic Health Record, automated diagnosis coding of patient notes is a useful task, but a challenging one due to the large number of codes and the length of patient notes. We investigate four models for assigning multiple ICD codes to discharge summaries taken from both MI…


 SUBIC: A Supervised Bi-Clustering Approach for Precision Medicine

Traditional medicine typically applies one-size-fits-all treatment for the entire patient population whereas precision medicine develops tailored treatment schemes for different patient subgroups. The fact that some factors may be more significant for a specific patient subgroup motivates clinician…


 Unifying PAC and Regret: Uniform PAC Bounds for Episodic Reinforcement Learning

 

Statistical performance bounds for reinforcement learning (RL) algorithms can be critical for high-stakes applications like healthcare. This paper introduces a new framework for theoretically measuring the performance of such algorithms called Uniform-PAC, which is a strengthening of the classical …


 Dose Prediction with U-net: A Feasibility Study for Predicting Dose Distributions from Contours using Deep Learning on Prostate IMRT Patients

 

With the advancement of treatment modalities in radiation therapy, outcomes haves greatly improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would alleviate this issue by guiding clinical plan optimization to save time a…


 Catching Anomalous Distributed Photovoltaics: An Edge-based Multi-modal Anomaly Detection

 

A significant challenge in energy system cyber security is the current inability to detect cyber-physical attacks targeting and originating from distributed grid-edge devices such as photovoltaics (PV) panels, smart flexible loads, and electric vehicles. We address this concern by designing and dev…


 Mining a Sub-Matrix of Maximal Sum

Biclustering techniques have been widely used to identify homogeneous subgroups within large data matrices, such as subsets of genes similarly expressed across subsets of patients. Mining a max-sum sub-matrix is a related but distinct problem for which one looks for a (non-necessarily contiguous) r…


 Discovery Radiomics via Deep Multi-Column Radiomic Sequencers for Skin Cancer Detection

While skin cancer is the most diagnosed form of cancer in men and women, with more cases diagnosed each year than all other cancers combined, sufficiently early diagnosis results in very good prognosis and as such makes early detection crucial. While radiomics have shown considerable promise as a p…


 Cross-modal Recurrent Models for Human Weight Objective Prediction from Multimodal Time-series Data

  

We analyse multimodal time-series data corresponding to weight, sleep and steps measurements, derived from a dataset spanning 15000 users, collected across a range of consumer-grade health devices by Nokia Digital Health – Withings. We focus on predicting whether a user will successfully achi…


 EMR-based medical knowledge representation and inference via Markov random fields and distributed representation learning

Objective: Electronic medical records (EMRs) contain an amount of medical knowledge which can be used for clinical decision support (CDS). Our objective is a general system that can extract and represent these knowledge contained in EMRs to support three CDS tasks: test recommendation, initial diag…


 A textual transform of multivariate time-series for prognostics

Prognostics or early detection of incipient faults is an important industrial challenge for condition-based and preventive maintenance. Physics-based approaches to modeling fault progression are infeasible due to multiple interacting components, uncontrolled environmental factors and observability …


 Why Pay More When You Can Pay Less: A Joint Learning Framework for Active Feature Acquisition and Classification

  

We consider the problem of active feature acquisition, where we sequentially select the subset of features in order to achieve the maximum prediction performance in the most cost-effective way. In this work, we formulate this active feature acquisition problem as a reinforcement learning problem, a…


 A constrained L1 minimization approach for estimating multiple Sparse Gaussian or Nonparanormal Graphical Models

Identifying context-specific entity networks from aggregated data is an important task, arising often in bioinformatics and neuroimaging. Computationally, this task can be formulated as jointly estimating multiple different, but related, sparse Undirected Graphical Models (UGM) from aggregated samp…


 Depression Scale Recognition from Audio, Visual and Text Analysis

      

Depression is a major mental health disorder that is rapidly affecting lives worldwide. Depression not only impacts emotional but also physical and psychological state of the person. Its symptoms include lack of interest in daily activities, feeling low, anxiety, frustration, loss of weight and eve…


 Neonatal Seizure Detection using Convolutional Neural Networks

  

This study presents a novel end-to-end architecture that learns hierarchical representations from raw EEG data using fully convolutional deep neural networks for the task of neonatal seizure detection. The deep neural network acts as both feature extractor and classifier, allowing for end-to-end op…


 DeepLung: 3D Deep Convolutional Nets for Automated Pulmonary Nodule Detection and Classification

 

In this work, we present a fully automated lung CT cancer diagnosis system, DeepLung. DeepLung contains two parts, nodule detection and classification. Considering the 3D nature of lung CT data, two 3D networks are designed for the nodule detection and classification respectively. Specifically, a 3…


 Co-training for Demographic Classification Using Deep Learning from Label Proportions

   

Deep learning algorithms have recently produced state-of-the-art accuracy in many classification tasks, but this success is typically dependent on access to many annotated training examples. For domains without such data, an attractive alternative is to train models with light, or distant supervisi…


 Multi-view Graph Embedding with Hub Detection for Brain Network Analysis

 

Multi-view graph embedding has become a widely studied problem in the area of graph learning. Most of the existing works on multi-view graph embedding aim to find a shared common node embedding across all the views of the graph by combining the different views in a specific way. Hub detection, as a…


 False arrhythmia alarm reduction in the intensive care unit

Research has shown that false alarms constitute more than 80% of the alarms triggered in the intensive care unit (ICU). The high false arrhythmia alarm rate has severe implications such as disruption of patient care, caregiver alarm fatigue, and desensitization from clinical staff to real life-thre…


 UI-Net: Interactive Artificial Neural Networks for Iterative Image Segmentation Based on a User Model

 

For complex segmentation tasks, fully automatic systems are inherently limited in their achievable accuracy for extracting relevant objects. Especially in cases where only few data sets need to be processed for a highly accurate result, semi-automatic segmentation techniques exhibit a clear benefit…