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 Deceased Organ Matching in Australia

Despite efforts to increase the supply of organs from living donors, most kidney transplants performed in Australia still come from deceased donors. The age of these donated organs has increased substantially in recent decades as the rate of fatal accidents on roads has fallen. The Organ and Tissue…


 Replacement AutoEncoder: A Privacy-Preserving Algorithm for Sensory Data Analysis

  

An increasing number of sensors on mobile, Internet of things (IoT), and wearable devices generate time-series measurements of physical activities. Though access to the sensory data is critical to the success of many beneficial applications such as health monitoring or activity recognition, a wide …


 Beat by Beat: Classifying Cardiac Arrhythmias with Recurrent Neural Networks

 

With tens of thousands of electrocardiogram (ECG) records processed by mobile cardiac event recorders every day, heart rhythm classification algorithms are an important tool for the continuous monitoring of patients at risk. We utilise an annotated dataset of 12,186 single-lead ECG recordings to bu…


 Using artificial intelligence to improve early breast cancer detection

Model developed at MIT’s Computer Science and Artificial Intelligence Laboratory could reduce false positives and unnecessary surgeries. Using artificial intelligence to improve early breast cancer detection by Adam Conner-Simons | CSAIL


 Safe Medicine Recommendation via Medical Knowledge Graph Embedding

Most of the existing medicine recommendation systems that are mainly based on electronic medical records (EMRs) are significantly assisting doctors to make better clinical decisions benefiting both patients and caregivers. Even though the growth of EMRs is at a lighting fast speed in the era of big…


 Checkpoint Ensembles: Ensemble Methods from a Single Training Process

   

We present the checkpoint ensembles method that can learn ensemble models on a single training process. Although checkpoint ensembles can be applied to any parametric iterative learning technique, here we focus on neural networks. Neural networks’ composable and simple neurons make it possibl…


 Protein identification with deep learning: from abc to xyz

    

Proteins are the main workhorses of biological functions in a cell, a tissue, or an organism. Identification and quantification of proteins in a given sample, e.g. a cell type under normal/disease conditions, are fundamental tasks for the understanding of human health and disease. In this paper, we…


 Meta Inverse Reinforcement Learning via Maximum Reward Sharing for Human Motion Analysis`

  

This work handles the inverse reinforcement learning (IRL) problem where only a small number of demonstrations are available from a demonstrator for each high-dimensional task, insufficient toestimate an accurate reward function. Observing that each demonstrator has an inherent reward for each stat…


 End-to-end Training for Whole Image Breast Cancer Diagnosis using An All Convolutional Design

 

We develop an end-to-end training algorithm for whole-image breast cancer diagnosis based on mammograms. It requires lesion annotations only at the first stage of training. After that, a whole image classifier can be trained using only image level labels. This greatly reduced the reliance on lesion…


 The use of neural networks in the analysis of sleep stages and the diagnosis of narcolepsy

We used neural networks in ~3,000 sleep recordings from over 10 locations to automate sleep stage scoring, producing a probability distribution called an hypnodensity graph. Accuracy was validated in 70 subjects scored by six technicians (gold standard). Our best model performed better than any ind…


 Constructing multi-modality and multi-classifier radiomics predictive models through reliable classifier fusion

Radiomics aims to extract and analyze large numbers of quantitative features from medical images and is highly promising in staging, diagnosing, and predicting outcomes of cancer treatments. Nevertheless, several challenges need to be addressed to construct an optimal radiomics predictive model. Fi…


 Modular Representation of Layered Neural Networks

   

Layered neural networks have greatly improved the performance of various applications including image processing, speech recognition, natural language processing, and bioinformatics. However, it is still difficult to discover or interpret knowledge from the inference provided by a layered neural ne…


 Indexing the Event Calculus with Kd-trees to Monitor Diabetes

Personal Health Systems (PHS) are mobile solutions tailored to monitoring patients affected by chronic non communicable diseases. A patient affected by a chronic disease can generate large amounts of events. Type 1 Diabetic patients generate several glucose events per day, ranging from at least 6 e…


 A Workflow for Visual Diagnostics of Binary Classifiers using Instance-Level Explanations

Human-in-the-loop data analysis applications necessitate greater transparency in machine learning models for experts to understand and trust their decisions. To this end, we propose a visual analytics workflow to help data scientists and domain experts explore, diagnose, and understand the decision…


 Upper Bound of Bayesian Generalization Error in Non-negative Matrix Factorization

  

Non-negative matrix factorization (NMF) is a new knowledge discovery method that is used for text mining, signal processing, bioinformatics, and consumer analysis. However, its basic property as a learning machine is not yet clarified, as it is not a regular statistical model, resulting that theore…


 Recognizing Detailed Human Context In-the-Wild from Smartphones and Smartwatches

The ability to automatically recognize a person’s behavioral context can contribute to health monitoring, aging care and many other domains. Validating context recognition in-the-wild is crucial to promote practical applications that work in real-life settings. We collected over 300k minutes …


 Toward Scalable Machine Learning and Data Mining: the Bioinformatics Case

 

In an effort to overcome the data deluge in computational biology and bioinformatics and to facilitate bioinformatics research in the era of big data, we identify some of the most influential algorithms that have been widely used in the bioinformatics community. These top data mining and machine le…


 Multi-Label Classification of Patient Notes a Case Study on ICD Code Assignment

In the context of the Electronic Health Record, automated diagnosis coding of patient notes is a useful task, but a challenging one due to the large number of codes and the length of patient notes. We investigate four models for assigning multiple ICD codes to discharge summaries taken from both MI…


 SUBIC: A Supervised Bi-Clustering Approach for Precision Medicine

Traditional medicine typically applies one-size-fits-all treatment for the entire patient population whereas precision medicine develops tailored treatment schemes for different patient subgroups. The fact that some factors may be more significant for a specific patient subgroup motivates clinician…


 Unifying PAC and Regret: Uniform PAC Bounds for Episodic Reinforcement Learning

 

Statistical performance bounds for reinforcement learning (RL) algorithms can be critical for high-stakes applications like healthcare. This paper introduces a new framework for theoretically measuring the performance of such algorithms called Uniform-PAC, which is a strengthening of the classical …


 Dose Prediction with U-net: A Feasibility Study for Predicting Dose Distributions from Contours using Deep Learning on Prostate IMRT Patients

 

With the advancement of treatment modalities in radiation therapy, outcomes haves greatly improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would alleviate this issue by guiding clinical plan optimization to save time a…


 Catching Anomalous Distributed Photovoltaics: An Edge-based Multi-modal Anomaly Detection

 

A significant challenge in energy system cyber security is the current inability to detect cyber-physical attacks targeting and originating from distributed grid-edge devices such as photovoltaics (PV) panels, smart flexible loads, and electric vehicles. We address this concern by designing and dev…


 Mining a Sub-Matrix of Maximal Sum

Biclustering techniques have been widely used to identify homogeneous subgroups within large data matrices, such as subsets of genes similarly expressed across subsets of patients. Mining a max-sum sub-matrix is a related but distinct problem for which one looks for a (non-necessarily contiguous) r…


 Discovery Radiomics via Deep Multi-Column Radiomic Sequencers for Skin Cancer Detection

While skin cancer is the most diagnosed form of cancer in men and women, with more cases diagnosed each year than all other cancers combined, sufficiently early diagnosis results in very good prognosis and as such makes early detection crucial. While radiomics have shown considerable promise as a p…


 Cross-modal Recurrent Models for Human Weight Objective Prediction from Multimodal Time-series Data

  

We analyse multimodal time-series data corresponding to weight, sleep and steps measurements, derived from a dataset spanning 15000 users, collected across a range of consumer-grade health devices by Nokia Digital Health – Withings. We focus on predicting whether a user will successfully achi…